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Peptide record

TPDB11827

Antibacterial Toxicity standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11827
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 39-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RNFFKRIRRAGKRIRKAIISAAPAVETLAQAQKIIKGGD
Physicochemical Analysis
C193H335N65O49
CHMWY
A
4350.19
12.42
11
2
17
+9
9.59
-0.387
95.38
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
5
Residue Composition
number
7
A
6
R
1
N
1
D
0
C
1
E
2
Q
3
G
0
H
6
I
1
L
5
K
0
M
2
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 7 R: 6 N: 1 D: 1 C: 0 E: 1 Q: 2 G: 3 H: 0 I: 6 L: 1 K: 5 M: 0 F: 2 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
39
C193H335N65O49
4350.19
12.42
+9
9.59
-0.387
Evidence Records 2 records
Evidence 1 Activity

Activity

6.88% Hemolysis
Toxicity
115 µM
Hemolytic Cytotoxic
6.88% Hemolysis | 115 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity and interactions of cationic peptides derived from Galleria mellonella cecropin D-like peptide with model membranes. | J Antibiot (Tokyo) | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
735.4 µM
Hemolytic Cytotoxic
50% Hemolysis | 735.4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity and interactions of cationic peptides derived from Galleria mellonella cecropin D-like peptide with model membranes. | J Antibiot (Tokyo) | 2017