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Peptide record

TPDB11810

Antibacterial Anticancer Antifungal Antiparasitic standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB11810
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia Antifungipept CAFPdb
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SICCSFPDPWGGLCCEDHCSYIGKPGGQCSDKGVCTCN
Physicochemical Analysis
C163H245N45O55S8
ARM
C
3971.49
4.44
3
4
7
-2
4.77
-0.145
38.42
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7490
188.59
16
Residue Composition
number
0
A
0
R
1
N
3
D
8
C
1
E
1
Q
6
G
1
H
2
I
1
L
2
K
0
M
1
F
3
P
4
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 3 C: 8 E: 1 Q: 1 G: 6 H: 1 I: 2 L: 1 K: 2 M: 0 F: 1 P: 3 S: 4 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
38
C163H245N45O55S8
3971.49
4.44
-2
4.77
-0.145
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

B. subtilis DSM 10

Source & Reference

NA

Other

The activity has been demonstrated. Active against Gram+ B. subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 1
Evidence 2 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

M. luteus DSM 20030

Source & Reference

NA

Other

monstrated. Active against Gram+ B. subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 1
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. auricularis DSM 20609

Source & Reference

NA

Other

subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64
Evidence 4 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

erium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 10041
Evidence 5 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Streptococcus pyogenes ATCC 12344

Source & Reference

NA

Other

ularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

A. bohemicus DSM 100419

Source & Reference

NA

Other

CC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml). No activity at 64 ug/ml against E-faecalis AT
Evidence 7 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Y. mollaretii DSM 18520

Source & Reference

NA

Other

, S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml). No activity at 64 ug/ml against E-faecalis ATCC 29212, E-coli K12 DSM 498, and P-fluores
Evidence 8 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

B. subtilis DSM 10

Source & Reference

CAFPdb Antifungipept

Other

The activity has been demonstrated. Active against Gram+ B. subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 1
Evidence 9 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

M. luteus DSM 20030

Source & Reference

CAFPdb Antifungipept

Other

monstrated. Active against Gram+ B. subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 1
Evidence 10 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

S. auricularis DSM 20609

Source & Reference

CAFPdb Antifungipept

Other

subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64
Evidence 11 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

CAFPdb Antifungipept

Other

erium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 10041
Evidence 12 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Streptococcus pyogenes ATCC 12344

Source & Reference

CAFPdb Antifungipept

Other

ularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml).
Evidence 13 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

A. bohemicus DSM 100419

Source & Reference

CAFPdb Antifungipept

Other

CC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml). No activity at 64 ug/ml against E-faecalis AT
Evidence 14 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Y. mollaretii DSM 18520

Source & Reference

CAFPdb Antifungipept

Other

, S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml). No activity at 64 ug/ml against E-faecalis ATCC 29212, E-coli K12 DSM 498, and P-fluores
Evidence 15 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

B. subtilis DSM 10

Source & Reference

NA

Other

The activity has been demonstrated. Active against Gram+ B. subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 1
Evidence 16 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

M. luteus DSM 20030

Source & Reference

NA

Other

monstrated. Active against Gram+ B. subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 1
Evidence 17 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

S. auricularis DSM 20609

Source & Reference

NA

Other

subtilis DSM 10 (MIC 16 ug/ml), B. megaterium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64
Evidence 18 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

erium DSM 32, M. luteus DSM 20030 (MIC 4 ug/ml), S. auricularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 10041
Evidence 19 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

Streptococcus pyogenes ATCC 12344

Source & Reference

NA

Other

ularis DSM 20609 (MIC 16 ug/ml), S. aureus ATCC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml).
Evidence 20 Activity

Activity

MIC
Antiparasitic
32 µg/mL

Target

A. bohemicus DSM 100419

Source & Reference

NA

Other

CC 25923 (MIC 8 ug/ml), MRSA (MIC 16 ug/ml), S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml). No activity at 64 ug/ml against E-faecalis AT
Evidence 21 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

Y. mollaretii DSM 18520

Source & Reference

NA

Other

, S. pyogenes ATCC 12344 (MIC 64 ug/ml), Gram- A. bohemicus DSM 100419 (MIC 32 ug/ml) and Y. mollaretii DSM 18520 (MIC 64 ug/ml). No activity at 64 ug/ml against E-faecalis ATCC 29212, E-coli K12 DSM 498, and P-fluores