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Peptide record

TPDB11808

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB11808
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGCPWNRYQCHSHCRSIGRLGGYCAGSLRLTCTCYRS
Physicochemical Analysis
C180H274N60O50S6
DEKMV
CG
4270.89
8.88
7
0
10
+5
-1.12
-0.363
43.68
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
10345
242.22
17
Residue Composition
number
1
A
5
R
1
N
0
D
6
C
0
E
1
Q
6
G
2
H
1
I
3
L
0
K
0
M
1
F
1
P
4
S
2
T
1
W
3
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 1 D: 0 C: 6 E: 0 Q: 1 G: 6 H: 2 I: 1 L: 3 K: 0 M: 0 F: 1 P: 1 S: 4 T: 2 W: 1 Y: 3 V: 0
Chemical Descriptors
38
C180H274N60O50S6
4270.89
8.88
+5
-1.12
-0.363
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

Staphylococcus aureus ATCC 43300 or ATCC 25923 or E48

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Gram- E. coli D31 (MEC 1.8 uM), and V. parahemolyticus (MEC 3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyic
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. pseudintermedius A2101

Source & Reference

dbAMP DRAMP

Other

3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermi
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Streptococcus agalactiae ATCC 13813

Source & Reference

dbAMP DRAMP

Other

TCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MI
Evidence 4 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. hyicus NCTC 10350

Source & Reference

dbAMP DRAMP

Other

ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >6
Evidence 5 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

Staphylococcus epidermidis ATCC 35984 or ATCC 12228 or G-81

Source & Reference

dbAMP DRAMP

Other

IC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >64 ug/ml), S-typhimurium CVCC 14028 (MIC >64 ug/ml), and S-flexn
Evidence 6 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

Staphylococcus aureus ATCC 43300 or ATCC 25923 or E48

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Gram- E. coli D31 (MEC 1.8 uM), and V. parahemolyticus (MEC 3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyic
Evidence 7 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

S. pseudintermedius A2101

Source & Reference

dbAMP DRAMP Antifungipept

Other

3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermi
Evidence 8 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Streptococcus agalactiae ATCC 13813

Source & Reference

dbAMP DRAMP Antifungipept

Other

TCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MI
Evidence 9 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

S. hyicus NCTC 10350

Source & Reference

dbAMP DRAMP Antifungipept

Other

ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >6
Evidence 10 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Staphylococcus epidermidis ATCC 35984 or ATCC 12228 or G-81

Source & Reference

dbAMP DRAMP Antifungipept

Other

IC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >64 ug/ml), S-typhimurium CVCC 14028 (MIC >64 ug/ml), and S-flexn
Evidence 11 Activity

Activity

MIC
Antiparasitic
8-16 µg/mL

Target

Staphylococcus aureus ATCC 43300 or ATCC 25923 or E48

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Gram- E. coli D31 (MEC 1.8 uM), and V. parahemolyticus (MEC 3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyic
Evidence 12 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

S. pseudintermedius A2101

Source & Reference

DRAMP

Other

3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermi
Evidence 13 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

Streptococcus agalactiae ATCC 13813

Source & Reference

DRAMP

Other

TCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MI
Evidence 14 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

S. hyicus NCTC 10350

Source & Reference

DRAMP

Other

ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >6
Evidence 15 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

Staphylococcus epidermidis ATCC 35984 or ATCC 12228 or G-81

Source & Reference

DRAMP

Other

IC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >64 ug/ml), S-typhimurium CVCC 14028 (MIC >64 ug/ml), and S-flexn
Evidence 16 Activity

Activity

MIC
Antiviral
8-16 µg/mL

Target

Staphylococcus aureus ATCC 43300 or ATCC 25923 or E48

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Gram- E. coli D31 (MEC 1.8 uM), and V. parahemolyticus (MEC 3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyic
Evidence 17 Activity

Activity

MIC
Antiviral
8 µg/mL

Target

S. pseudintermedius A2101

Source & Reference

DRAMP

Other

3.5 uM). Also active against S. aureus ATCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermi
Evidence 18 Activity

Activity

MIC
Antiviral
4 µg/mL

Target

Streptococcus agalactiae ATCC 13813

Source & Reference

DRAMP

Other

TCC 43300 or ATCC 25923 or E48 (MIC 8-16 ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MI
Evidence 19 Activity

Activity

MIC
Antiviral
16 µg/mL

Target

S. hyicus NCTC 10350

Source & Reference

DRAMP

Other

ug/ml), S. pseudintermedius A2101 (MIC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >6
Evidence 20 Activity

Activity

MIC
Antiviral
4 µg/mL

Target

Staphylococcus epidermidis ATCC 35984 or ATCC 12228 or G-81

Source & Reference

DRAMP

Other

IC 8 ug/ml), S. agalactiae ATCC 13813 (MIC 4 ug/ml), S. hyicus NCTC 10350 (MIC 16 ug/ml), S. epidermidis ATCC 35984 or ATCC 12228 or G-81 (MIC 4 ug/ml), E-coli ATCC 25922 (MIC >64 ug/ml), S-typhimurium CVCC 14028 (MIC >64 ug/ml), and S-flexn