Back to search

Peptide record

TPDB11807

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
38 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11807
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb dbAMP 3.0
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGCPLNQGACHNHCRSIGRRGGYCAGIIKQTCTCYRK
Physicochemical Analysis
C171H274N60O48S6
DEMWV
G
4130.79
9.25
8
0
9
+6
3.79
-0.439
46.32
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
81.22
15
Residue Composition
number
2
A
4
R
2
N
0
D
6
C
0
E
2
Q
7
G
2
H
3
I
1
L
2
K
0
M
1
F
1
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 2 D: 0 C: 6 E: 0 Q: 2 G: 7 H: 2 I: 3 L: 1 K: 2 M: 0 F: 1 P: 1 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
38
C171H274N60O48S6
4130.79
9.25
+6
3.79
-0.439
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Both longicin and longicin P4 are active against E. coli, P. aeruginosa, S. aureus, and S. typhimurium. Active against equine parasite B. equi and canine B. gibsoni. Longicin mature peptide corresponds to residues 37 to 73 of the precursor protein. Longicin P4 corresponds to 53-73 (i.e., C-terminal fragment). Other inactive peptides include longicin P1 (residues 23-37), longicin P2 (residues 33-45), and longicin P3 (42-57).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Both longicin and longicin P4 are active against E. coli, P. aeruginosa, S. aureus, and S. typhimurium. Active against equine parasite B. equi and canine B. gibsoni. Longicin mature peptide corresponds to residues 37 to 73 of the precursor protein. Longicin P4 corresponds to 53-73 (i.e., C-terminal fragment). Other inactive peptides include longicin P1 (residues 23-37), longicin P2 (residues 33-45), and longicin P3 (42-57).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Both longicin and longicin P4 are active against E. coli, P. aeruginosa, S. aureus, and S. typhimurium. Active against equine parasite B. equi and canine B. gibsoni. Longicin mature peptide corresponds to residues 37 to 73 of the precursor protein. Longicin P4 corresponds to 53-73 (i.e., C-terminal fragment). Other inactive peptides include longicin P1 (residues 23-37), longicin P2 (residues 33-45), and longicin P3 (42-57).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Both longicin and longicin P4 are active against E. coli, P. aeruginosa, S. aureus, and S. typhimurium. Active against equine parasite B. equi and canine B. gibsoni. Longicin mature peptide corresponds to residues 37 to 73 of the precursor protein. Longicin P4 corresponds to 53-73 (i.e., C-terminal fragment). Other inactive peptides include longicin P1 (residues 23-37), longicin P2 (residues 33-45), and longicin P3 (42-57).