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Peptide record

TPDB11803

Antibacterial Anticancer Antifungal Antiparasitic standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB11803
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
NPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK
Physicochemical Analysis
C169H302N58O45S7
DEHLFWY
C
4091.04
10.39
9
0
10
+9
8.98
-0.092
71.58
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
375
9.17
12
Residue Composition
number
1
A
4
R
2
N
0
D
6
C
0
E
1
Q
4
G
0
H
3
I
0
L
5
K
1
M
0
F
3
P
2
S
1
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 0 C: 6 E: 0 Q: 1 G: 4 H: 0 I: 3 L: 0 K: 5 M: 1 F: 0 P: 3 S: 2 T: 1 W: 0 Y: 0 V: 5
Chemical Descriptors
38
C169H302N58O45S7
4091.04
10.39
+9
8.98
-0.092
Evidence Records 15 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12-25 µg/mL

Target

Escherichia coli D31

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. a
Evidence 2 Activity

Activity

MIC
Antibacterial
12-25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP

Other

Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. a
Evidence 3 Activity

Activity

MIC
Antibacterial
25-50 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP

Other

Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
25-50 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP DRAMP

Other

/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
6-12 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP DRAMP

Other

/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
12-25 µg/mL

Target

Escherichia coli D31

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. a
Evidence 7 Activity

Activity

MIC
Antifungal
12-25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. a
Evidence 8 Activity

Activity

MIC
Antifungal
25-50 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 9 Activity

Activity

MIC
Antifungal
25-50 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
6-12 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiparasitic
12-25 µg/mL

Target

Escherichia coli D31

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. a
Evidence 12 Activity

Activity

MIC
Antiparasitic
12-25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

DRAMP

Other

Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. a
Evidence 13 Activity

Activity

MIC
Antiparasitic
25-50 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

DRAMP

Other

Active against E. coli D31 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 14 Activity

Activity

MIC
Antiparasitic
25-50 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

DRAMP

Other

/ml), K. pneumoniae ATCC 13883 (MIC 12-25 ug/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).
Evidence 15 Activity

Activity

MIC
Antiparasitic
6-12 µg/mL

Target

Candida albicans ATCC 14053

Source & Reference

DRAMP

Other

/ml), S. aureus ATCC 25923 (MIC 25-50 ug/ml), P. aeruginosa ATCC 27853 (MIC 25-50 ug/ml), C. albicans ATCC 14053 (MIC 6-12 ug/ml).