Back to search

Peptide record

TPDB11801

Antibacterial Anticancer Antifungal Antiparasitic standard

38 amino acids

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB11801

Activity

Antibacterial Anticancer Antifungal Antiparasitic

Activity_category_statistics

Anti-infective peptides Cancer-related peptides

Database_Source

AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb

Sequence_Type

standard

Has_Modification No

Description A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.

Sequence

KVPIGAIKKGGKIIKKGLGVLGAAGTAHEVYNHVRNRQ

FASTA

>TPDB11801|Antibacterial;Anticancer;Antifungal;Antiparasitic|length=38
KVPIGAIKKGGKIIKKGLGVLGAAGTAHEVYNHVRNRQ

Formula C178H305N57O46

Absent Amino Acids DCMFSW

Common Amino Acids G

Mass 3979.73

PI 11.19

Basic Residues 10

Acidic Residues 1

Hydrophobic Residues 15

Net Charge +7

Boman Index 9.88

Hydrophobicity -0.253

Aliphatic Index 102.63

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 1490

Absorbance 280nm 37.44

Polar Residues 5

number

Amino Acid Distribution

A: 4 R: 2 N: 2 D: 0 C: 0 E: 1 Q: 1 G: 7 H: 2 I: 4 L: 2 K: 6 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 4

Length

Formula

C178H305N57O46

Mass

3979.73

11.19

Net Charge

Boman Index

9.88

Hydrophobicity

-0.253

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP DRAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 u

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 100 µM

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 u

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1 µM

Target

Target Organism F. graminearum

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (myc

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

ia E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 100 µM

Target

Target Organism A. rabiei

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 8 µM

Target

Target Organism L. maculans

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

ngi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.nige

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 8 µM

Target

Target Organism F. graminearum

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

xysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 8 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

biei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement >150 µM

Target

Target Organism A.niger

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 10 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 u

Evidence 11 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 100 µM

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 u

Evidence 12 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1 µM

Target

Target Organism F. graminearum

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (myc

Evidence 13 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Evidence 14 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 100 µM

Target

Target Organism A. rabiei

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Evidence 15 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 8 µM

Target

Target Organism L. maculans

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 8 µM

Target

Target Organism F. graminearum

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

xysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 8 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

biei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement >150 µM

Target

Target Organism A.niger

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10 µM

Target

Target Organism Escherichia coli

Source & Reference

Database Source DRAMP

Other

Source Activity Label	Source Definition
Antiparasitic	DRAMP antiparasitic activity supported by activity records against parasitic targets.

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 u

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 100 µM

Target

Target Organism M. luteus

Source & Reference

Database Source DRAMP

Other

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 u

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 1 µM

Target

Target Organism F. graminearum

Source & Reference

Database Source DRAMP

Other

Evidence Text

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (myc

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source DRAMP

Other

Evidence Text

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 100 µM

Target

Target Organism A. rabiei

Source & Reference

Database Source DRAMP

Other

Evidence Text

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 8 µM

Target

Target Organism L. maculans

Source & Reference

Database Source DRAMP

Other

Evidence Text

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 8 µM

Target

Target Organism F. graminearum

Source & Reference

Database Source DRAMP

Other

Evidence Text

xysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 8 µM

Target

Target Organism F. oxysporum

Source & Reference

Database Source DRAMP

Other

Evidence Text

biei (MIC 100 uM), L. maculans (MIC 8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement >150 µM

Target

Target Organism A.niger

Source & Reference

Database Source DRAMP

Other

Evidence Text

8 uM), and fungi (mycelia) F. graminearum (MIC 8 uM), F. oxysporum (MIC 8 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021