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Peptide record

TPDB11800

Antibacterial Anticancer Antifungal Antiparasitic standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB11800
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KVPIGAIKKGGKIIKKGLGVIGAAGTAHEVYSHVKNRH
Physicochemical Analysis
C178H303N55O45
DCQMFW
GK
3933.71
10.94
11
1
15
+7
10.40
-0.139
102.63
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
37.88
4
Residue Composition
number
4
A
1
R
1
N
0
D
0
C
1
E
0
Q
7
G
3
H
5
I
1
L
7
K
0
M
0
F
1
P
1
S
1
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 7 H: 3 I: 5 L: 1 K: 7 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 1 V: 4
Chemical Descriptors
38
C178H303N55O45
3933.71
10.94
+7
10.40
-0.139
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 u
Evidence 2 Activity

Activity

MIC
Antibacterial
100 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 u
Evidence 3 Activity

Activity

MIC
Antibacterial
1 µM

Target

F. graminearum

Source & Reference

dbAMP DRAMP

Other

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.ni
Evidence 4 Activity

Activity

MIC
Antibacterial
10 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP

Other

ia E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated
Evidence 5 Activity

Activity

MIC
Antibacterial
100 µM

Target

A. rabiei

Source & Reference

dbAMP DRAMP

Other

luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antibacterial
6 µM

Target

L. maculans

Source & Reference

dbAMP DRAMP

Other

ngi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antibacterial
>150 µM

Target

A.niger

Source & Reference

dbAMP DRAMP

Other

uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 8 Activity

Activity

MIC
Antifungal
10 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 u
Evidence 9 Activity

Activity

MIC
Antifungal
100 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 u
Evidence 10 Activity

Activity

MIC
Antifungal
1 µM

Target

F. graminearum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.ni
Evidence 11 Activity

Activity

MIC
Antifungal
10 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ia E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated
Evidence 12 Activity

Activity

MIC
Antifungal
100 µM

Target

A. rabiei

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 13 Activity

Activity

MIC
Antifungal
6 µM

Target

L. maculans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ngi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 14 Activity

Activity

MIC
Antifungal
>150 µM

Target

A.niger

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 15 Activity

Activity

MIC
Antiparasitic
10 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 u
Evidence 16 Activity

Activity

MIC
Antiparasitic
100 µM

Target

M. luteus

Source & Reference

DRAMP

Other

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 u
Evidence 17 Activity

Activity

MIC
Antiparasitic
1 µM

Target

F. graminearum

Source & Reference

DRAMP

Other

Active against bacteria E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.ni
Evidence 18 Activity

Activity

MIC
Antiparasitic
10 µM

Target

F. oxysporum

Source & Reference

DRAMP

Other

ia E. coli (MIC 10 uM), M. luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated
Evidence 19 Activity

Activity

MIC
Antiparasitic
100 µM

Target

A. rabiei

Source & Reference

DRAMP

Other

luteus (MIC 100 uM), fungi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 20 Activity

Activity

MIC
Antiparasitic
6 µM

Target

L. maculans

Source & Reference

DRAMP

Other

ngi (spore): F. graminearum (MIC 1 uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021
Evidence 21 Activity

Activity

MIC
Antiparasitic
>150 µM

Target

A.niger

Source & Reference

DRAMP

Other

uM), F. oxysporum (MIC 10 uM), A. rabiei (MIC 100 uM), L. maculans (MIC 6 uM). Inactive: A.niger (MIC>150 uM). Updated 7/2021