Back to search

Peptide record

TPDB11796

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11796
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGCPLNQGACHRHCRSIRRRGGYCAGFFKQTCTCYRN
Physicochemical Analysis
C181H279N65O48S6
DEMWV
RCG
4325.97
9.70
9
0
9
+7
2.77
-0.653
25.79
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
77.55
15
Residue Composition
number
2
A
6
R
2
N
0
D
6
C
0
E
2
Q
6
G
2
H
1
I
1
L
1
K
0
M
3
F
1
P
1
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 2 D: 0 C: 6 E: 0 Q: 2 G: 6 H: 2 I: 1 L: 1 K: 1 M: 0 F: 3 P: 1 S: 1 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
38
C181H279N65O48S6
4325.97
9.70
+7
2.77
-0.653
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.25-1 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against S. aureus (MIC 0.25-1 uM) and S. epidermidis (MIC 0.33-0.42 uM). Warning: other bacteria not tested.
Evidence 2 Activity

Activity

MIC
Antibacterial
0.33-0.42 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

active against S. aureus (MIC 0.25-1 uM) and S. epidermidis (MIC 0.33-0.42 uM). Warning: other bacteria not tested.
Evidence 3 Activity

Activity

MIC
Antifungal
0.25-1 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against S. aureus (MIC 0.25-1 uM) and S. epidermidis (MIC 0.33-0.42 uM). Warning: other bacteria not tested.
Evidence 4 Activity

Activity

MIC
Antifungal
0.33-0.42 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP Antifungipept

Other

active against S. aureus (MIC 0.25-1 uM) and S. epidermidis (MIC 0.33-0.42 uM). Warning: other bacteria not tested.
Evidence 5 Activity

Activity

MIC
Antiparasitic
0.25-1 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against S. aureus (MIC 0.25-1 uM) and S. epidermidis (MIC 0.33-0.42 uM). Warning: other bacteria not tested.
Evidence 6 Activity

Activity

MIC
Antiparasitic
0.33-0.42 µM

Target

Staphylococcus epidermidis

Source & Reference

DRAMP

Other

active against S. aureus (MIC 0.25-1 uM) and S. epidermidis (MIC 0.33-0.42 uM). Warning: other bacteria not tested.
Evidence 7 Activity

Activity

1% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
1% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010