Back to search

Peptide record

TPDB11787

Antibacterial Antifungal Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11787
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 38-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GRLRNLIEKAGQNIRGKIQGIGRRIKDILKNLQPRPQV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C189H337N67O50
CHMFSTWY
RI
4348.17
12.41
10
2
12
+8
2.88
-0.818
112.89
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
1
A
6
R
3
N
1
D
0
C
1
E
4
Q
5
G
0
H
6
I
4
L
4
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 3 D: 1 C: 0 E: 1 Q: 4 G: 5 H: 0 I: 6 L: 4 K: 4 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
38 reviewed residue count
C189H337N67O50 sequence-only estimate (linear, free termini)
4348.17 sequence-only estimate (linear, free termini)
12.41 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
2.88 sequence-only estimate (linear, free termini)
-0.818 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The cathelicidin-like peptide derived from panda genome is a potential antimicrobial peptide. | Gene | 2012
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 200 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
The cathelicidin-like peptide derived from panda genome is a potential antimicrobial peptide. | Gene | 2012