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Peptide record

TPDB11786

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB11786
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFGCPLNQGACHNHCRSIRRRGGYCSGIIKQTCTCYRN
Physicochemical Analysis
C173H277N63O50S6
DEMWV
CG
4231.85
9.27
8
0
8
+6
4.32
-0.605
43.68
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
79.28
17
Residue Composition
number
1
A
5
R
3
N
0
D
6
C
0
E
2
Q
6
G
2
H
3
I
1
L
1
K
0
M
1
F
1
P
2
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 3 D: 0 C: 6 E: 0 Q: 2 G: 6 H: 2 I: 3 L: 1 K: 1 M: 0 F: 1 P: 1 S: 2 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
38
C173H277N63O50S6
4231.85
9.27
+6
4.32
-0.605
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
<5% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Defensin from the ornate sheep tick Dermacentor marginatus and its effect on Lyme borreliosis spirochetes. | Dev Comp Immunol | 2014