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Peptide record

TPDB11771

Antibacterial Antifungal Antiparasitic Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB11771
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP dbAMP 3.0 i2APP
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
EWRPHGSIGGSGLRPGRPQTLPPQRPRRPDFNGPRHRF
Physicochemical Analysis
C192H298N70O49
ACKMYV
RP
4370.92
12.62
10
2
6
+6
11.75
-1.595
30.79
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
5500
125.83
6
Residue Composition
number
0
A
8
R
1
N
1
D
0
C
1
E
2
Q
6
G
2
H
1
I
2
L
0
K
0
M
2
F
8
P
2
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 1 D: 1 C: 0 E: 1 Q: 2 G: 6 H: 2 I: 1 L: 2 K: 0 M: 0 F: 2 P: 8 S: 2 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
38
C192H298N70O49
4370.92
12.62
+6
11.75
-1.595
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
It exhibited inhibitory activity against the blood-stage P. falciparum parasite. 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
It exhibited inhibitory activity against the blood-stage P. falciparum parasite. 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
It exhibited inhibitory activity against the blood-stage P. falciparum parasite. 7/2021
Evidence 4 Activity

Activity

10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
10% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019
Evidence 5 Activity

Activity

<10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<10% Hemolysis | 100 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019