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Peptide record

TPDB11757

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB11757
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RLKELITTGGQKIGEKIRRIGQRIKDFFKNLQPREEKS
Physicochemical Analysis
C199H341N63O56
ACHMWYV
K
4512.29
11.10
11
5
10
+6
16.87
-1.139
82.11
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
7
Residue Composition
number
0
A
5
R
1
N
1
D
0
C
4
E
3
Q
4
G
0
H
5
I
3
L
6
K
0
M
2
F
1
P
1
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 1 C: 0 E: 4 Q: 3 G: 4 H: 0 I: 5 L: 3 K: 6 M: 0 F: 2 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
38
C199H341N63O56
4512.29
11.10
+6
16.87
-1.139
Evidence Records 4 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
5% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Canine cathelicidin (K9CATH): gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide. | Dev Comp Immunol | 2007
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
5% Hemolysis | 100 | µM | target cell: Chicken erythrocytes

Target

Chicken erythrocytes

Source & Reference

NA
DBAASP
Canine cathelicidin (K9CATH): gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide. | Dev Comp Immunol | 2007
Evidence 3 Activity

Activity

5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
5% Hemolysis | 100 | µM | target cell: Dog erythrocytes

Target

Dog erythrocytes

Source & Reference

NA
DBAASP
Canine cathelicidin (K9CATH): gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide. | Dev Comp Immunol | 2007
Evidence 4 Activity

Activity

13% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
13% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011