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Peptide record

TPDB11742

Antibacterial Anticancer Antifungal Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11742
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
TFKRKNGSRKNGHRPGGYSLIALGNKKVLKAPYMESI
Physicochemical Analysis
C183H303N57O49S1
DCQW
K
4117.83
11.20
10
1
12
+8
8.28
-0.868
65.95
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
2980
72.37
9
Residue Composition
number
2
A
3
R
3
N
0
D
0
C
1
E
0
Q
5
G
1
H
2
I
3
L
6
K
1
M
1
F
2
P
3
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 3 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 1 I: 2 L: 3 K: 6 M: 1 F: 1 P: 2 S: 3 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
37
C183H303N57O49S1
4117.83
11.20
+8
8.28
-0.868
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
1-500 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 1-500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes:5% Hemolysis=1-500µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2016 Oct 11 6:35019.