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Peptide record

TPDB11737

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11737
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIFSALAAGVKLLGNTLFKMAGKAGAEHLACKATNQC
Physicochemical Analysis
C163H270N46O46S3
RDPWY
A
3706.40
9.72
5
1
18
+3
1.45
0.476
92.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.37
8
Residue Composition
number
8
A
0
R
2
N
0
D
2
C
1
E
1
Q
5
G
1
H
1
I
5
L
4
K
1
M
2
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 8 R: 0 N: 2 D: 0 C: 2 E: 1 Q: 1 G: 5 H: 1 I: 1 L: 5 K: 4 M: 1 F: 2 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C163H270N46O46S3
3706.40
9.72
+3
1.45
0.476
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
35 µM
Hemolytic Cytotoxic
50% Hemolysis | 35 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host defense peptides in skin secretions of the Oregon spotted frog Rana pretiosa: implications for species resistance to chytridiomycosis. | Dev Comp Immunol | 2011
Evidence 2 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.