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Peptide record

TPDB11734

Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11734
Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia AntiBP3 dbAMP AFP-GFuse Antifungipept CAFPdb AVPpred-BWR
standard
No
A 37-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, Anticancer, and other sources) peptide sequence curated from Peptipedia, AntiBP3, dbAMP, and other sources, with an available 3D structural model.
Sequence
RWKIFKKIEKVGRNVRDGIIKAGPAVAVVGQAATVVK
Physicochemical Analysis
C183H313N55O45
CHLMSY
V
4003.84
11.62
9
2
18
+7
8.67
0.095
110.54
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
137.37
3
Residue Composition
number
5
A
3
R
1
N
1
D
0
C
1
E
1
Q
4
G
0
H
4
I
0
L
6
K
0
M
1
F
1
P
0
S
1
T
1
W
0
Y
7
V
Amino Acid Distribution
A: 5 R: 3 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 4 H: 0 I: 4 L: 0 K: 6 M: 0 F: 1 P: 1 S: 0 T: 1 W: 1 Y: 0 V: 7
Chemical Descriptors
37
C183H313N55O45
4003.84
11.62
+7
8.67
0.095
Evidence Records 25 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.25 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
al spectrum, it is especially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B
Evidence 2 Activity

Activity

MIC
Antibacterial
0.50 µM

Target

S. typhimurium

Source & Reference

dbAMP

Other

cially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S.
Evidence 3 Activity

Activity

MIC
Antibacterial
1.0 um

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

ative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
32 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

m- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
16 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
2.0 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP

Other

M), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
0.25 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
al spectrum, it is especially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B
Evidence 8 Activity

Activity

MIC
Antifungal
0.50 µM

Target

S. typhimurium

Source & Reference

dbAMP CAFPdb Antifungipept

Other

cially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S.
Evidence 9 Activity

Activity

MIC
Antifungal
1.0 um

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
32 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

m- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 11 Activity

Activity

MIC
Antifungal
16 µM

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 12 Activity

Activity

MIC
Antifungal
2.0 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

M), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 13 Activity

Activity

MIC
Antiparasitic
0.25 µM

Target

Escherichia coli

Source & Reference

NA

Other

al spectrum, it is especially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B
Evidence 14 Activity

Activity

MIC
Antiparasitic
0.50 µM

Target

S. typhimurium

Source & Reference

NA

Other

cially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S.
Evidence 15 Activity

Activity

MIC
Antiparasitic
1.0 um

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

ative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 16 Activity

Activity

MIC
Antiparasitic
32 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

m- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 17 Activity

Activity

MIC
Antiparasitic
16 µM

Target

B. subtilis

Source & Reference

NA

Other

), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 18 Activity

Activity

MIC
Antiparasitic
2.0 µM

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

M), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 19 Activity

Activity

MIC
Antiviral
0.25 µM

Target

Escherichia coli

Source & Reference

NA

Other

al spectrum, it is especially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B
Evidence 20 Activity

Activity

MIC
Antiviral
0.50 µM

Target

S. typhimurium

Source & Reference

NA

Other

cially active against Gram-negative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S.
Evidence 21 Activity

Activity

MIC
Antiviral
1.0 um

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

ative bacteria. Active against Gram- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 22 Activity

Activity

MIC
Antiviral
32 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

m- E. coli (MIC 0.25 uM), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 23 Activity

Activity

MIC
Antiviral
16 µM

Target

B. subtilis

Source & Reference

NA

Other

), S. typhimurium (MIC 0.50 uM), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 24 Activity

Activity

MIC
Antiviral
2.0 µM

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

M), P. aeruginosa (MIC 1.0 um), Gram+ S. aureus (MIC 32 uM), B. subtilis (MIC 16 uM), and S. epidermidis (MIC 2.0 uM).
Evidence 25 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptoid-Substituted Hybrid Antimicrobial Peptide Derived from Papiliocin and Magainin 2 with Enhanced Bacterial Selectivity and Anti-inflammatory Activity. | Biochemistry | 2015