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Peptide record

TPDB11730

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11730
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIFSLIKTAAKFVGKNLLKQAGKAGVEHLACKANNQC
Physicochemical Analysis
C172H288N50O47S2
RDMPWY
AK
3872.61
10.27
7
1
16
+5
5.17
0.089
95.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.23
9
Residue Composition
number
6
A
0
R
3
N
0
D
2
C
1
E
2
Q
4
G
1
H
2
I
4
L
6
K
0
M
2
F
0
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 6 R: 0 N: 3 D: 0 C: 2 E: 1 Q: 2 G: 4 H: 1 I: 2 L: 4 K: 6 M: 0 F: 2 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
37
C172H288N50O47S2
3872.61
10.27
+5
5.17
0.089
Evidence Records 4 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
17 %
[Ref:19843479] It has 17% hemolytic activity at 100 µg/mL against rabbit red blood cells

Target

rabbit red blood cells

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan 155(1):72-76.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

17% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
17% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Five novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis | Comp Biochem Physiol B Biochem Mol Biol | 2010
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:19843479] It has 17% hemolytic activity at 100 µg/mL against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan 155(1):72-76.
Evidence 4 Hemolysis

Activity

17 %
% Hemolysis
[Ref:19843479] It has 17% hemolytic activity at 100 µg/mL against rabbit red blood cells
Hemolysis

Target

rabbit red blood cells

Source & Reference

APD_complete HemoPI PD_Hemolysis
Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan 155(1):72-76.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.