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Peptide record

TPDB11728

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11728
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIFALIKTAAKFVGKNLLKQAGKAGLEHLACKANNQC
Physicochemical Analysis
C173H290N50O46S2
RDMPSWY
A
3870.63
10.27
7
1
17
+5
4.24
0.149
100.54
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.23
8
Residue Composition
number
7
A
0
R
3
N
0
D
2
C
1
E
2
Q
4
G
1
H
2
I
5
L
6
K
0
M
2
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 7 R: 0 N: 3 D: 0 C: 2 E: 1 Q: 2 G: 4 H: 1 I: 2 L: 5 K: 6 M: 0 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C173H290N50O46S2
3870.63
10.27
+5
4.24
0.149
Evidence Records 4 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
22 %
[Ref:19843479] It has 22% hemolytic activity at 100 µg/mL against rabbit red blood cells

Target

rabbit red blood cells

Source & Reference

Hemolytik APD_complete PD_Hemolysis
DRAMP4
Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan 155(1):72-76.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. Hemolytik experimentally validated hemolytic peptide annotation.
Evidence 2 Activity

Activity

22% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
22% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Five novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis | Comp Biochem Physiol B Biochem Mol Biol | 2010
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:19843479] It has 22% hemolytic activity at 100 µg/mL against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan 155(1):72-76.
Evidence 4 Hemolysis

Activity

22 %
% Hemolysis
[Ref:19843479] It has 22% hemolytic activity at 100 µg/mL against rabbit red blood cells
Hemolysis

Target

rabbit red blood cells

Source & Reference

APD_complete HemoPI PD_Hemolysis
Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan 155(1):72-76.
DRAMP4
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.