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Peptide record

TPDB11721

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11721
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVFTLIKGATQLIGKTLGKELGKTGLELMACKITNQC
Physicochemical Analysis
C171H297N45O50S3
RDHPSWY
GL
3879.69
9.65
5
2
14
+3
4.93
0.295
108.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.22
10
Residue Composition
number
2
A
0
R
1
N
0
D
2
C
2
E
2
Q
6
G
0
H
3
I
6
L
5
K
1
M
1
F
0
P
0
S
5
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 2 E: 2 Q: 2 G: 6 H: 0 I: 3 L: 6 K: 5 M: 1 F: 1 P: 0 S: 0 T: 5 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C171H297N45O50S3
3879.69
9.65
+3
4.93
0.295
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
10.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
21.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

IC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 3 Activity

Activity

MIC
Antibacterial
10.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

led P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 4 Activity

Activity

MIC
Antifungal
10.8 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
21.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

IC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 6 Activity

Activity

MIC
Antifungal
10.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

led P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 7 Activity

Activity

MIC
Antiparasitic
10.8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
21.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 9 Activity

Activity

MIC
Antiparasitic
10.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1
Evidence 10 Activity

Activity

MIC
Antiviral
10.8 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
21.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

IC 10.8 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al
Evidence 12 Activity

Activity

MIC
Antiviral
10.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

led P. aeruginosa) (MIC 21.6 ug/ml), Gram+ bacteria S. aureus (MIC 21.6 ug/ml), and yeast C. albicans (MIC 10.8 ug/ml). Found in multiple species. Also see Yang X et al. 2012 J Proteome Res. J Proteome Res. 1