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Peptide record

TPDB11713

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11713
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLFTLIKGAAKLIGKTTAKEAGKTGKLEMACKITNQC
Physicochemical Analysis
C168H294N46O49S3
RDHPSWYV
K
3838.64
10.18
7
2
14
+5
6.86
0.016
87.30
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.26
9
Residue Composition
number
5
A
0
R
1
N
0
D
2
C
2
E
1
Q
5
G
0
H
3
I
4
L
7
K
1
M
1
F
0
P
0
S
5
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 1 D: 0 C: 2 E: 2 Q: 1 G: 5 H: 0 I: 3 L: 4 K: 7 M: 1 F: 1 P: 0 S: 0 T: 5 W: 0 Y: 0 V: 0
Chemical Descriptors
37
C168H294N46O49S3
3838.64
10.18
+5
6.86
0.016
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
2.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
4.4 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
4.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
2.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
4.4 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
4.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
2.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
4.4 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
4.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
2.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 4.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
4.4 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 2.2 ug/ml), Gram+ bacteria S. aureus (MIC 2.2 ug/ml), and yeast C. albicans (MIC 4.4 ug/ml). Updated 7/2021