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Peptide record

TPDB11708

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11708
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb i2APP APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKISGGC
Physicochemical Analysis
C162H281N45O47S2
RDHMPWY
G
3675.41
10.06
5
1
15
+4
4.35
0.559
115.68
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.40
9
Residue Composition
number
2
A
0
R
2
N
0
D
2
C
1
E
1
Q
7
G
0
H
1
I
5
L
5
K
0
M
1
F
0
P
3
S
1
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 0 N: 2 D: 0 C: 2 E: 1 Q: 1 G: 7 H: 0 I: 1 L: 5 K: 5 M: 0 F: 1 P: 0 S: 3 T: 1 W: 0 Y: 0 V: 6
Chemical Descriptors
37
C162H281N45O47S2
3675.41
10.06
+4
4.35
0.559
Evidence Records 2 records
Evidence 1 Activity

Activity

18% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
18% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Purification and characterization of antimicrobial peptides from the skin secretion of Rana dybowskii. | Peptides | 2007
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.