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Peptide record

TPDB11704

Antibacterial Antifungal Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11704
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIMRVFKGVLKTAGKSVAKNVAGSFLDRLKCKISGGC
Physicochemical Analysis
C169H292N50O45S3
EQHPWY
GK
3840.67
10.81
8
1
15
+7
4.30
0.276
92.16
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.25
7
Residue Composition
number
3
A
2
R
1
N
1
D
2
C
0
E
0
Q
6
G
0
H
2
I
3
L
6
K
1
M
2
F
0
P
3
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 2 N: 1 D: 1 C: 2 E: 0 Q: 0 G: 6 H: 0 I: 2 L: 3 K: 6 M: 1 F: 2 P: 0 S: 3 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
37
C169H292N50O45S3
3840.67
10.81
+7
4.30
0.276
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
52 µM
Hemolytic Cytotoxic
50% Hemolysis | 52 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning and functional characterization of novel antimicrobial peptides from the skin of brown frog, Rana zhenhaiensis. | Zoolog Sci | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis