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Peptide record

TPDB11701

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11701
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GLLSVFKGVLKTAGKNVAKNVAGSLLDQLKCKISGGC
Physicochemical Analysis
C164H286N46O47S2
REHMPWY
GLK
3718.47
10.27
6
1
15
+5
3.67
0.389
113.24
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.36
9
Residue Composition
number
3
A
0
R
2
N
1
D
2
C
0
E
1
Q
6
G
0
H
1
I
6
L
6
K
0
M
1
F
0
P
3
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 1 C: 2 E: 0 Q: 1 G: 6 H: 0 I: 1 L: 6 K: 6 M: 0 F: 1 P: 0 S: 3 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
37
C164H286N46O47S2
3718.47
10.27
+5
3.67
0.389
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
73 µM
Hemolytic Cytotoxic
50% Hemolysis | 73 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning of novel antimicrobial peptide genes from the skin of the Chinese brown frog, Rana chensinensis. | Zoolog Sci | 2011
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Curr Microbiol. 2014 Jun 68(6):685-92
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis