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Peptide record

TPDB11698

Antibacterial Antifungal Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11698
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GIFSLFKAGAKFFGKNLLKEAGKAGAEHLACKAANQC
Physicochemical Analysis
C174H276N48O46S2
RDMPTWYV
A
3840.52
9.98
7
2
17
+4
3.63
0.092
74.32
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.25
6
Residue Composition
number
8
A
0
R
2
N
0
D
2
C
2
E
1
Q
5
G
1
H
1
I
4
L
6
K
0
M
4
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 2 D: 0 C: 2 E: 2 Q: 1 G: 5 H: 1 I: 1 L: 4 K: 6 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
37
C174H276N48O46S2
3840.52
9.98
+4
3.63
0.092
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (IS) (MIC 200 uM), E. faecalis 981 (IS) (MIC 50 uM), N. asteroides 2011
Evidence 2 Activity

Activity

MIC
Antibacterial
>400 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

IC >400 uM), K.Pneumoniae 08040724 (IS) (MIC >400 uM), E.cloacae CGMCC 1.57 (MIC 400 uM), E.coli ATCC 25922 (MIC >400 uM), P. faecalis X29 (IS) (MIC 12.5 uM), C.glabrata 090902 (IS) (MIC >400 uM), C.albicans ATC
Evidence 3 Activity

Activity

MIC
Antibacterial
>400 µM

Target

C.albicans ATCC10231

Source & Reference

dbAMP

Other

(MIC >400 uM), P. faecalis X29 (IS) (MIC 12.5 uM), C.glabrata 090902 (IS) (MIC >400 uM), C.albicans ATCC10231 (MIC>400 uM). IS= Isolated strain.
Evidence 4 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC 25923 (MIC 12.5 uM), E.faecium 091299 (IS) (MIC 200 uM), E. faecalis 981 (IS) (MIC 50 uM), N. asteroides 2011
Evidence 5 Activity

Activity

MIC
Antifungal
>400 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC >400 uM), K.Pneumoniae 08040724 (IS) (MIC >400 uM), E.cloacae CGMCC 1.57 (MIC 400 uM), E.coli ATCC 25922 (MIC >400 uM), P. faecalis X29 (IS) (MIC 12.5 uM), C.glabrata 090902 (IS) (MIC >400 uM), C.albicans ATC
Evidence 6 Activity

Activity

MIC
Antifungal
>400 µM

Target

C.albicans ATCC10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC >400 uM), P. faecalis X29 (IS) (MIC 12.5 uM), C.glabrata 090902 (IS) (MIC >400 uM), C.albicans ATCC10231 (MIC>400 uM). IS= Isolated strain.
Evidence 7 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple antimicrobial peptides from the skin of fine-spined frog, Hylarana spinulosa (Ranidae). | Biochimie | 2013
Evidence 8 Activity

Activity

9% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
9% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple antimicrobial peptides from the skin of fine-spined frog, Hylarana spinulosa (Ranidae). | Biochimie | 2013