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Peptide record

TPDB11695

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11695
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LLGDFFRKAREKIGEEFKRIVQRIKDFLRNLVPRTES
Physicochemical Analysis
C204H335N61O54
CHMWY
R
4506.28
10.91
10
6
14
+4
13.38
-0.659
92.16
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
1
A
6
R
1
N
2
D
0
C
4
E
1
Q
2
G
0
H
3
I
4
L
4
K
0
M
4
F
1
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 6 N: 1 D: 2 C: 0 E: 4 Q: 1 G: 2 H: 0 I: 3 L: 4 K: 4 M: 0 F: 4 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
37
C204H335N61O54
4506.28
10.91
+4
13.38
-0.659
Evidence Records 3 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
100% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity | J Biol Chem | 2006
Evidence 2 Activity

Activity

25% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
25% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity | J Biol Chem | 2006
Evidence 3 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.