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Peptide record

TPDB11694

Antibacterial Antifungal Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11694
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKAILS
Physicochemical Analysis
C185H317N53O45S1
DCQHTY
K
4035.94
11.23
9
2
18
+7
7.53
0.032
110.81
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
136.28
3
Residue Composition
number
5
A
2
R
2
N
0
D
0
C
2
E
0
Q
4
G
0
H
5
I
2
L
7
K
1
M
1
F
1
P
1
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 5 R: 2 N: 2 D: 0 C: 0 E: 2 Q: 0 G: 4 H: 0 I: 5 L: 2 K: 7 M: 1 F: 1 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
37
C185H317N53O45S1
4035.94
11.23
+7
7.53
0.032
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.7-3.3 µM

Target

Escherichia coli BUE55 or NCTC11954

Source & Reference

NA

Other

ophilus, E. coli K12, B. megaterium, B. subtilis (inhibition zone assays). Microdilution: E. coli BUE55 or NCTC11954 (MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis
Evidence 2 Activity

Activity

MIC
Antibacterial
1.7 µM

Target

Bacteroides fragilis NCTC943

Source & Reference

NA

Other

lis (inhibition zone assays). Microdilution: E. coli BUE55 or NCTC11954 (MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore e
Evidence 3 Activity

Activity

MIC
Antibacterial
16.7 µM

Target

Pseudomonas aeruginosa NCTC10332

Source & Reference

NA

Other

odilution: E. coli BUE55 or NCTC11954 (MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram
Evidence 4 Activity

Activity

MIC
Antibacterial
33.3 µM

Target

Staphylococcus epidermidis NCTC 11047

Source & Reference

NA

Other

MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (M
Evidence 5 Activity

Activity

MIC
Antibacterial
0.6 µM

Target

L. anguillarum

Source & Reference

NA

Other

S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warn
Evidence 6 Activity

Activity

MIC
Antibacterial
0.5 µM

Target

Escherichia coli

Source & Reference

NA

Other

C 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warning: the C-terminus of
Evidence 7 Activity

Activity

MIC
Antibacterial
1.0 µM

Target

C. glutamicum

Source & Reference

NA

Other

996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warning: the C-terminus of the peptide made in this study is
Evidence 8 Activity

Activity

MIC
Antibacterial
9.4 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warning: the C-terminus of the peptide made in this study is slightly shorter than the o
Evidence 9 Activity

Activity

MIC
Antifungal
1.7-3.3 µM

Target

Escherichia coli BUE55 or NCTC11954

Source & Reference

Antifungipept

Other

ophilus, E. coli K12, B. megaterium, B. subtilis (inhibition zone assays). Microdilution: E. coli BUE55 or NCTC11954 (MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis
Evidence 10 Activity

Activity

MIC
Antifungal
1.7 µM

Target

Bacteroides fragilis NCTC943

Source & Reference

Antifungipept

Other

lis (inhibition zone assays). Microdilution: E. coli BUE55 or NCTC11954 (MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore e
Evidence 11 Activity

Activity

MIC
Antifungal
16.7 µM

Target

Pseudomonas aeruginosa NCTC10332

Source & Reference

Antifungipept

Other

odilution: E. coli BUE55 or NCTC11954 (MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram
Evidence 12 Activity

Activity

MIC
Antifungal
33.3 µM

Target

Staphylococcus epidermidis NCTC 11047

Source & Reference

Antifungipept

Other

MIC 1.7-3.3 uM), B. fragilis NCTC943 (MIC 1.7 uM), P. aeruginosa NCTC10332 (MIC 16.7 uM), S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (M
Evidence 13 Activity

Activity

MIC
Antifungal
0.6 µM

Target

L. anguillarum

Source & Reference

Antifungipept

Other

S. epidermidis NCTC 11047 (MIC 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warn
Evidence 14 Activity

Activity

MIC
Antifungal
0.5 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

C 33.3 uM) ( Moore et al., 1996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warning: the C-terminus of
Evidence 15 Activity

Activity

MIC
Antifungal
1.0 µM

Target

C. glutamicum

Source & Reference

Antifungipept

Other

996 ). Also Active against Gram- L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warning: the C-terminus of the peptide made in this study is
Evidence 16 Activity

Activity

MIC
Antifungal
9.4 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

L. anguillarum (MIC 0.6 uM), E. coli (MIC 0.5 uM), Gram+ C. glutamicum (MIC 1.0 uM), and S. aureus (MIC 9.4 uM). Warning: the C-terminus of the peptide made in this study is slightly shorter than the o