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Peptide record

TPDB11682

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11682
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SLGNFFRKARKKIGEEFKRIVQRIKDFLQHLIPRTEA
Physicochemical Analysis
C204H334N62O51
CMWY
RK
4471.28
11.46
11
4
14
+6
11.86
-0.681
87.03
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
2
A
5
R
1
N
1
D
0
C
3
E
2
Q
2
G
1
H
4
I
3
L
5
K
0
M
4
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 5 N: 1 D: 1 C: 0 E: 3 Q: 2 G: 2 H: 1 I: 4 L: 3 K: 5 M: 0 F: 4 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C204H334N62O51
4471.28
11.46
+6
11.86
-0.681
Evidence Records 3 records
Evidence 1 Activity

Activity

55% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
55% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity. | J Biol Chem | 2006
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
100% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity. | J Biol Chem | 2006
Evidence 3 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.