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Peptide record

TPDB11680

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11680
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RLGDILQKAREKIEGGLKKLVQKIKDFFGKFAPRTES
Physicochemical Analysis
C193H323N55O52
NCHMWY
K
4246.03
10.64
10
5
13
+5
12.97
-0.678
87.03
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
4
Residue Composition
number
2
A
3
R
0
N
2
D
0
C
3
E
2
Q
4
G
0
H
3
I
4
L
7
K
0
M
3
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 2 C: 0 E: 3 Q: 2 G: 4 H: 0 I: 3 L: 4 K: 7 M: 0 F: 3 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C193H323N55O52
4246.03
10.64
+5
12.97
-0.678
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
0% Hemolysis | 10 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity | J Biol Chem | 2006
Evidence 2 Activity

Activity

15% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
15% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity | J Biol Chem | 2006