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Peptide record

TPDB11677

Antibacterial Antifungal standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11677
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 37-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GYFPGRPPFPRPFPRPPSRPFPRPPFPGPFPRPYPWR
Physicochemical Analysis
C219H301N59O41
ANDCEQHILKMTV
P
4416.17
12.53
7
0
9
+7
2.97
-1.281
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
8480
192.02
3
Residue Composition
number
0
A
7
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
6
F
17
P
1
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 6 P: 17 S: 1 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
37
C219H301N59O41
4416.17
12.53
+7
2.97
-1.281
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.78-1.56 µM

Target

M. luteus ATCC9341

Source & Reference

NA

Other

A synthetic form is active against M. luteus ATCC9341 (MIC 0.78-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harvey
Evidence 2 Activity

Activity

MIC
Antibacterial
3.1-6.2 µM

Target

S. Typhimurium ATCC13311

Source & Reference

NA

Other

A synthetic form is active against M. luteus ATCC9341 (MIC 0.78-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyti
Evidence 3 Activity

Activity

MIC
Antibacterial
12.5-25 µM

Target

Escherichia coli ATCC35218

Source & Reference

NA

Other

against M. luteus ATCC9341 (MIC 0.78-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyticus ATCC17802 (MIC 3.1-6.2 uM). Reco
Evidence 4 Activity

Activity

MIC
Antibacterial
0.195-0.39 µM

Target

V. harveyi

Source & Reference

NA

Other

-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyticus ATCC17802 (MIC 3.1-6.2 uM). Recombinant peptide only showed acti
Evidence 5 Activity

Activity

MIC
Antibacterial
3.1-6.2 µM

Target

V. parahaemolyticus ATCC17802

Source & Reference

NA

Other

(MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyticus ATCC17802 (MIC 3.1-6.2 uM). Recombinant peptide only showed activity against M. luteus ATCC9341 (MIC 3.1-6.2 uM) and
Evidence 6 Activity

Activity

MIC
Antibacterial
3.1-6.2 µM

Target

M. luteus ATCC9341

Source & Reference

NA

Other

haemolyticus ATCC17802 (MIC 3.1-6.2 uM). Recombinant peptide only showed activity against M. luteus ATCC9341 (MIC 3.1-6.2 uM) and V. harveyi (MIC 1.56-3.13 uM). The reasons may be multiple and a possible sequence mo
Evidence 7 Activity

Activity

MIC
Antibacterial
1.56-3.13 µM

Target

V. harveyi

Source & Reference

NA

Other

Recombinant peptide only showed activity against M. luteus ATCC9341 (MIC 3.1-6.2 uM) and V. harveyi (MIC 1.56-3.13 uM). The reasons may be multiple and a possible sequence modification cannot not be excluded.
Evidence 8 Activity

Activity

MIC
Antifungal
0.78-1.56 µM

Target

M. luteus ATCC9341

Source & Reference

Antifungipept

Other

A synthetic form is active against M. luteus ATCC9341 (MIC 0.78-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harvey
Evidence 9 Activity

Activity

MIC
Antifungal
3.1-6.2 µM

Target

S. Typhimurium ATCC13311

Source & Reference

Antifungipept

Other

A synthetic form is active against M. luteus ATCC9341 (MIC 0.78-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyti
Evidence 10 Activity

Activity

MIC
Antifungal
12.5-25 µM

Target

Escherichia coli ATCC35218

Source & Reference

Antifungipept

Other

against M. luteus ATCC9341 (MIC 0.78-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyticus ATCC17802 (MIC 3.1-6.2 uM). Reco
Evidence 11 Activity

Activity

MIC
Antifungal
0.195-0.39 µM

Target

V. harveyi

Source & Reference

Antifungipept

Other

-1.56 uM), S. Typhimurium ATCC13311 (MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyticus ATCC17802 (MIC 3.1-6.2 uM). Recombinant peptide only showed acti
Evidence 12 Activity

Activity

MIC
Antifungal
3.1-6.2 µM

Target

V. parahaemolyticus ATCC17802

Source & Reference

Antifungipept

Other

(MIC 3.1-6.2 uM), E. coli ATCC35218 (MIC 12.5-25 uM), V. harveyi (MIC 0.195-0.39 uM), and V. parahaemolyticus ATCC17802 (MIC 3.1-6.2 uM). Recombinant peptide only showed activity against M. luteus ATCC9341 (MIC 3.1-6.2 uM) and
Evidence 13 Activity

Activity

MIC
Antifungal
3.1-6.2 µM

Target

M. luteus ATCC9341

Source & Reference

Antifungipept

Other

haemolyticus ATCC17802 (MIC 3.1-6.2 uM). Recombinant peptide only showed activity against M. luteus ATCC9341 (MIC 3.1-6.2 uM) and V. harveyi (MIC 1.56-3.13 uM). The reasons may be multiple and a possible sequence mo
Evidence 14 Activity

Activity

MIC
Antifungal
1.56-3.13 µM

Target

V. harveyi

Source & Reference

Antifungipept

Other

Recombinant peptide only showed activity against M. luteus ATCC9341 (MIC 3.1-6.2 uM) and V. harveyi (MIC 1.56-3.13 uM). The reasons may be multiple and a possible sequence modification cannot not be excluded.