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Peptide record

TPDB11669

Antibacterial Anticancer Antifungal Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11669
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KREDFLDQIIRDFRNFIYQKYRRLRDEFRKLRDILSG
Physicochemical Analysis
C217H345N67O58
ACHMPTWV
R
4820.54
10.52
11
7
14
+4
11.48
-1.138
84.32
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
61.82
6
Residue Composition
number
0
A
8
R
1
N
5
D
0
C
2
E
2
Q
1
G
0
H
4
I
4
L
3
K
0
M
4
F
0
P
1
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 1 D: 5 C: 0 E: 2 Q: 2 G: 1 H: 0 I: 4 L: 4 K: 3 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
37
C217H345N67O58
4820.54
10.52
+4
11.48
-1.138
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
1-500 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 1-500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes:5% Hemolysis=1-500µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Rep. 2016 Oct 11 6:35019.