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Peptide record

TPDB11663

Antibacterial Anticancer Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11663
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GFSSIFRGVAKFASKGLGKDLAKLGVDLVASKISKQS
Physicochemical Analysis
C173H289N47O49
NCEHMPTWY
KS
3811.48
10.82
7
2
16
+5
3.90
0.195
97.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
4
A
1
R
0
N
2
D
0
C
0
E
1
Q
5
G
0
H
2
I
4
L
6
K
0
M
3
F
0
P
6
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 5 H: 0 I: 2 L: 4 K: 6 M: 0 F: 3 P: 0 S: 6 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
37
C173H289N47O49
3811.48
10.82
+5
3.90
0.195
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Esculentin-2CHa: a host-defense peptide with differential cytotoxicity against bacteria, erythrocytes and tumor cells. | Peptides | 2013
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis>200 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2013 Jan 39:95-102.
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis