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Peptide record

TPDB11659

Antibacterial Antifungal Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11659
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
SLFSIFKTAAKFVGKNLLKQAGKAGLETLACKAKNEC
Physicochemical Analysis
C177H295N47O49S2
RDHMPWY
K
3929.69
10.18
7
2
16
+5
5.03
0.078
87.30
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.18
9
Residue Composition
number
6
A
0
R
2
N
0
D
2
C
2
E
1
Q
3
G
0
H
1
I
5
L
7
K
0
M
3
F
0
P
2
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 2 D: 0 C: 2 E: 2 Q: 1 G: 3 H: 0 I: 1 L: 5 K: 7 M: 0 F: 3 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C177H295N47O49S2
3929.69
10.18
+5
5.03
0.078
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
19 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
ive bacteria: R. rhodochrous X15 (IS) (MIC 1.2 uM), B. licheniformis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS (IS)(MIC 1.2 uM), S. aureus ATCC 25923(MIC 9 uM), E. coli ATCC 25922 (MI
Evidence 2 Activity

Activity

MIC
Antibacterial
9 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

ormis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS (IS)(MIC 1.2 uM), S. aureus ATCC 25923(MIC 9 uM), E. coli ATCC 25922 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 1105
Evidence 3 Activity

Activity

MIC
Antibacterial
75 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

ecalis 981 (MIC 19 uM), S. carnosus KHS (IS)(MIC 1.2 uM), S. aureus ATCC 25923(MIC 9 uM), E. coli ATCC 25922 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 4 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP

Other

0724 (IS)(MIC 150 uM), P. faecalis X29 (IS)(MIC 4.5 uM), S. rubidaea X01 (IS)(MIC 1.2uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 4.5 uM). IS: Isolated strain.
Evidence 5 Activity

Activity

MIC
Antifungal
19 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
ive bacteria: R. rhodochrous X15 (IS) (MIC 1.2 uM), B. licheniformis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS (IS)(MIC 1.2 uM), S. aureus ATCC 25923(MIC 9 uM), E. coli ATCC 25922 (MI
Evidence 6 Activity

Activity

MIC
Antifungal
9 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ormis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 19 uM), S. carnosus KHS (IS)(MIC 1.2 uM), S. aureus ATCC 25923(MIC 9 uM), E. coli ATCC 25922 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 1105
Evidence 7 Activity

Activity

MIC
Antifungal
75 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ecalis 981 (MIC 19 uM), S. carnosus KHS (IS)(MIC 1.2 uM), S. aureus ATCC 25923(MIC 9 uM), E. coli ATCC 25922 (MIC 75 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 8 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

0724 (IS)(MIC 150 uM), P. faecalis X29 (IS)(MIC 4.5 uM), S. rubidaea X01 (IS)(MIC 1.2uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 4.5 uM). IS: Isolated strain.
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
75 µM
Hemolytic Cytotoxic
50% Hemolysis | 75 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis | Peptides | 2012
Evidence 10 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.