Back to search

Peptide record

TPDB11651

Antibacterial Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11651
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 DRAMP Peptipedia
standard
No
A 37-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, DRAMP, and Peptipedia, with an available 3D structural model.
Sequence
KWKLFKKIHKVGQNIRKGIIKAGPAVAVVGQAAQIAK
Physicochemical Analysis
C186H317N55O42
DCEMSTY
K
3995.91
11.97
10
0
18
+9
6.51
-0.008
110.81
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
137.64
4
Residue Composition
number
6
A
1
R
1
N
0
D
0
C
0
E
3
Q
4
G
1
H
5
I
1
L
8
K
0
M
1
F
1
P
0
S
0
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 6 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 3 G: 4 H: 1 I: 5 L: 1 K: 8 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 4
Chemical Descriptors
37
C186H317N55O42
3995.91
11.97
+9
6.51
-0.008
Evidence Records 4 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Design, expression, and characterization of a novel cecropin A-derived peptide with high antibacterial activity. | Appl Microbiol Biotechnol | 2019
Evidence 2 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antibiofilm property and multiple action of peptide PEW300 against Pseudomonas aeruginosa | Front Microbiol | 2022
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Antibiofilm property and multiple action of peptide PEW300 against Pseudomonas aeruginosa | Front Microbiol | 2022
Evidence 4 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.30607494]non-hemolysis to Sheep erythrocytes up to 224 µg/ml.

Target

erythrocytes

Source & Reference

NA
DRAMP
Appl Microbiol Biotechnol. 2019 Feb 103(4):1765-1775.