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Peptide record

TPDB11648

Antibacterial Anticancer Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11648
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GFSSIFRGVAKFASKGLGKKLAKLGVKLVACKISKQC
Physicochemical Analysis
C177H303N49O43S2
NDEHMPTWY
K
3869.78
10.98
9
0
16
+9
2.68
0.351
97.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.23
7
Residue Composition
number
4
A
1
R
0
N
0
D
2
C
0
E
1
Q
5
G
0
H
2
I
4
L
8
K
0
M
3
F
0
P
4
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 5 H: 0 I: 2 L: 4 K: 8 M: 0 F: 3 P: 0 S: 4 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
37
C177H303N49O43S2
3869.78
10.98
+9
2.68
0.351
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
11 µM
Hemolytic Cytotoxic
50% Hemolysis | 11 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Esculentin-2CHa: a host-defense peptide with differential cytotoxicity against bacteria, erythrocytes and tumor cells. | Peptides | 2013
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis=11 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2013 Jan 39:95-102.
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis