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Peptide record

TPDB11647

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB11647
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GVFTLLKGATQLIGKTLGKELGKTGLELMACKITNQC
Physicochemical Analysis
C171H297N45O50S3
RDHPSWY
L
3879.69
9.65
5
2
14
+3
4.68
0.276
108.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.22
10
Residue Composition
number
2
A
0
R
1
N
0
D
2
C
2
E
2
Q
6
G
0
H
2
I
7
L
5
K
1
M
1
F
0
P
0
S
5
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 2 E: 2 Q: 2 G: 6 H: 0 I: 2 L: 7 K: 5 M: 1 F: 1 P: 0 S: 0 T: 5 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C171H297N45O50S3
3879.69
9.65
+3
4.68
0.276
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
7.9 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
7.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
15.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
7.9 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
7.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
15.8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
7.9 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
7.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
15.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
7.9 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
7.9 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 7.9 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
15.8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 7.9 ug/ml), Gram+ bacteria S. aureus (MIC 7.9 ug/ml), and yeast C. albicans (MIC 15.8 ug/ml). Updated 7/2021