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Peptide record

TPDB11639

Antibacterial Antifungal standard
36 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11639
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 36-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GFGCPNEWRCNAHCKRNRFRGGYCDSWFRRRCHCYG
Physicochemical Analysis
C187H269N67O47S6
QILMTV
R
4399.97
9.27
10
2
8
+6
3.14
-1.192
2.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
14355
326.25
12
Residue Composition
number
1
A
7
R
3
N
1
D
6
C
1
E
0
Q
5
G
2
H
0
I
0
L
1
K
0
M
3
F
1
P
1
S
0
T
2
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 7 N: 3 D: 1 C: 6 E: 1 Q: 0 G: 5 H: 2 I: 0 L: 0 K: 1 M: 0 F: 3 P: 1 S: 1 T: 0 W: 2 Y: 2 V: 0
Chemical Descriptors
36
C187H269N67O47S6
4399.97
9.27
+6
3.14
-1.192
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>250 µM

Target

P.aeruginosa

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram- bacteria E.coli (MIC > 250 uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), a
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

e against Gram- bacteria E.coli (MIC > 250 uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) an
Evidence 3 Activity

Activity

MIC
Antibacterial
8 µM

Target

L. grayi

Source & Reference

dbAMP

Other

ia E.coli (MIC > 250 uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5
Evidence 4 Activity

Activity

MIC
Antibacterial
>250 µM

Target

S.epidermidis

Source & Reference

dbAMP

Other

uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5 uM). 7/2021
Evidence 5 Activity

Activity

MIC
Antibacterial
5 µM

Target

F. graminearum

Source & Reference

dbAMP

Other

acteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5 uM). 7/2021
Evidence 6 Activity

Activity

MIC
Antibacterial
5 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5 uM). 7/2021
Evidence 7 Activity

Activity

MIC
Antifungal
>250 µM

Target

P.aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram- bacteria E.coli (MIC > 250 uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), a
Evidence 8 Activity

Activity

MIC
Antifungal
8 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

e against Gram- bacteria E.coli (MIC > 250 uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) an
Evidence 9 Activity

Activity

MIC
Antifungal
8 µM

Target

L. grayi

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ia E.coli (MIC > 250 uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5
Evidence 10 Activity

Activity

MIC
Antifungal
>250 µM

Target

S.epidermidis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

uM), P.aeruginosa (MIC>250 uM), Gram+ bacteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5 uM). 7/2021
Evidence 11 Activity

Activity

MIC
Antifungal
5 µM

Target

F. graminearum

Source & Reference

dbAMP CAFPdb Antifungipept

Other

acteria S. aureus (MIC 8 uM), L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5 uM). 7/2021
Evidence 12 Activity

Activity

MIC
Antifungal
5 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

L. grayi (MIC 8 uM), S.epidermidis (MIC >250 uM), and fungi F. graminearum (MIC 5 uM) and C. albicans (MIC 5 uM). 7/2021