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Peptide record

TPDB11630

Antibacterial Anticancer Antifungal Antiparasitic standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB11630
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifungipept
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
WNPFKELERAGQRVRDAIISAGPAVATVAQATALAK
Physicochemical Analysis
C169H277N51O49
CHMY
A
3807.37
10.56
5
3
18
+2
6.55
-0.033
92.50
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
144.46
6
Residue Composition
number
9
A
3
R
1
N
1
D
0
C
2
E
2
Q
2
G
0
H
2
I
2
L
2
K
0
M
1
F
2
P
1
S
2
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 9 R: 3 N: 1 D: 1 C: 0 E: 2 Q: 2 G: 2 H: 0 I: 2 L: 2 K: 2 M: 0 F: 1 P: 2 S: 1 T: 2 W: 1 Y: 0 V: 3
Chemical Descriptors
36
C169H277N51O49
3807.37
10.56
+2
6.55
-0.033
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Lethal concentrations against E. coli D21 or D31 (0.21-0.37 uM), S. marsescens Strain 12 (6.1 uM), P.aeruginosa (>81 uM), B.subtilis (>81 uM), B. megaterium (24 uM), B.thuringiensis (>81 uM), S.fecalis (>81 uM), and M. luteus (4 uM). UPdated 10/2020
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Lethal concentrations against E. coli D21 or D31 (0.21-0.37 uM), S. marsescens Strain 12 (6.1 uM), P.aeruginosa (>81 uM), B.subtilis (>81 uM), B. megaterium (24 uM), B.thuringiensis (>81 uM), S.fecalis (>81 uM), and M. luteus (4 uM). UPdated 10/2020
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Lethal concentrations against E. coli D21 or D31 (0.21-0.37 uM), S. marsescens Strain 12 (6.1 uM), P.aeruginosa (>81 uM), B.subtilis (>81 uM), B. megaterium (24 uM), B.thuringiensis (>81 uM), S.fecalis (>81 uM), and M. luteus (4 uM). UPdated 10/2020