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Peptide record

TPDB11615

Antibacterial Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB11615
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 36-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKVLKKKIMKMLRNRINGLVKAGPALKVKLQALAL
Physicochemical Analysis
C190H341N55O40S2
DCEHFSTY
K
4100.26
12.48
11
0
19
+11
5.10
0.036
132.78
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
134.14
3
Residue Composition
number
4
A
2
R
2
N
0
D
0
C
0
E
1
Q
2
G
0
H
2
I
7
L
9
K
2
M
0
F
1
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 2 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 7 K: 9 M: 2 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
36
C190H341N55O40S2
4100.26
12.48
+11
5.10
0.036
Evidence Records 1 records
Evidence 1 Activity

Activity

<1% Hemolysis
Toxicity
>250 µM
Hemolytic Cytotoxic
<1% Hemolysis | >250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms | Sci Rep | 2018