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Peptide record

TPDB11612

Antibacterial Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB11612
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 36-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
SPIHARYQRGVIPGPRWPYYRVGSGSGLKSVRNRWA
Physicochemical Analysis
C187H287N61O46
DCEMFT
R
4125.72
12.12
8
0
13
+7
2.35
-0.817
62.22
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
15470
374.97
9
Residue Composition
number
2
A
6
R
1
N
0
D
0
C
0
E
1
Q
5
G
1
H
2
I
1
L
1
K
0
M
0
F
4
P
4
S
0
T
2
W
3
Y
3
V
Amino Acid Distribution
A: 2 R: 6 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 5 H: 1 I: 2 L: 1 K: 1 M: 0 F: 0 P: 4 S: 4 T: 0 W: 2 Y: 3 V: 3
Chemical Descriptors
36
C187H287N61O46
4125.72
12.12
+7
2.35
-0.817
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>42.5 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | >42.5 | µg/mL | target cell: Chicken erythrocytes

Target

Chicken erythrocytes

Source & Reference

NA
DBAASP
Expression in Pichia Pastoris and biological activity of Avian ?-defensin 6 and its mutant peptide without cysteines. | Protein Pept Lett | 2012