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Peptide record

TPDB11609

Antibacterial Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB11609
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 36-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RICSRGKNCVSRPGVGSIIGRPGGGSLIGRPGGGSV
Physicochemical Analysis
C143H251N53O43S2
ADEQHMFTWY
G
3465.02
12.23
6
0
8
+6
5.50
-0.103
78.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
3.61
8
Residue Composition
number
0
A
5
R
1
N
0
D
2
C
0
E
0
Q
11
G
0
H
4
I
1
L
1
K
0
M
0
F
3
P
5
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 11 H: 0 I: 4 L: 1 K: 1 M: 0 F: 0 P: 3 S: 5 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
36
C143H251N53O43S2
3465.02
12.23
+6
5.50
-0.103
Evidence Records 3 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
2% Hemolysis | 256 | µM | target cell: Trout erythrocytes

Target

Trout erythrocytes

Source & Reference

NA
DBAASP
Identification of a novel cathelicidin gene in the rainbow trout, Oncorhynchus mykiss. | Infect Immun | 2005
Evidence 2 Activity

Activity

6% Hemolysis
Toxicity
1280 µM
Hemolytic Cytotoxic
6% Hemolysis | 1280 | µM | target cell: Trout erythrocytes

Target

Trout erythrocytes

Source & Reference

NA
DBAASP
Identification of a novel cathelicidin gene in the rainbow trout, Oncorhynchus mykiss. | Infect Immun | 2005
Evidence 3 Activity

Activity

8% Hemolysis
Toxicity
2560 µM
Hemolytic Cytotoxic
8% Hemolysis | 2560 | µM | target cell: Trout erythrocytes

Target

Trout erythrocytes

Source & Reference

NA
DBAASP
Identification of a novel cathelicidin gene in the rainbow trout, Oncorhynchus mykiss. | Infect Immun | 2005