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Peptide record

TPDB11599

Antibacterial Hemolysis Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB11599
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
SIGSALKKALPVAKKIGKIALPIAKAALPVAAGLVG
Physicochemical Analysis
C161H288N42O39
RNDCEQHMFTWY
A
3436.32
11.21
6
0
21
+6
2.23
0.956
146.67
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
9
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
4
I
5
L
6
K
0
M
0
F
3
P
2
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 9 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 4 L: 5 K: 6 M: 0 F: 0 P: 3 S: 2 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
36
C161H288N42O39
3436.32
11.21
+6
2.23
0.956
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
110 µM
Hemolytic Cytotoxic
100% Hemolysis | 110 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial activity and pore-forming properties of ceratotoxins: a mechanism of action based on the barrel stave model. | Biochim Biophys Acta | 2004
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis