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Peptide record

TPDB11594

Antibacterial Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11594
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
EAQNLEKEIAALEQAIQGLEKEIPALAQQIQALEL
Physicochemical Analysis
C169H284N44O57
RDCHMFSTWYV
AE
3844.37
3.86
2
7
17
-5
14.69
-0.154
131.43
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
7
Residue Composition
number
7
A
0
R
1
N
0
D
0
C
7
E
6
Q
1
G
0
H
4
I
6
L
2
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 0 C: 0 E: 7 Q: 6 G: 1 H: 0 I: 4 L: 6 K: 2 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
35
C169H284N44O57
3844.37
3.86
-5
14.69
-0.154
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>>250 µM
Hemolytic Cytotoxic
50% Hemolysis | >>250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-antimicrobial Peptides: Folding-Mediated Host Defense Antagonists | J Biol Chem | 2013