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Peptide record

TPDB11590

Ep-AMP1 Antibacterial Anticancer Antifungal standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11590
Ep-AMP1
Antibacterial Anticancer Antifungal
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia CancerPPD 2.0 Antifungipept CAFPdb dbAMP
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
CVLIGQRCDNDRGPRCCSGQGNCVPLPFLGGVCAV
Physicochemical Analysis
C148H244N48O45S6
EHKMTWY
CG
3608.22
7.63
3
2
10
+1
3.98
0.280
80.57
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
375
10.39
11
Residue Composition
number
1
A
3
R
2
N
2
D
6
C
0
E
2
Q
6
G
0
H
1
I
3
L
0
K
0
M
1
F
3
P
1
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 3 N: 2 D: 2 C: 6 E: 0 Q: 2 G: 6 H: 0 I: 1 L: 3 K: 0 M: 0 F: 1 P: 3 S: 1 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
35
C148H244N48O45S6
3608.22
7.63
+1
3.98
0.280
Cyclized
L
Cyclic
Cyclized
Antibacterial and Anticancer
Echinopsis pachanoi
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 > 100 µM
Anticancer
100 µM

Target

Lymphoma cancer
U-937/GTB
Blood

Assay & Model

Fluorometric microculture cytotoxicity assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2015

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.