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Peptide record

TPDB11588

Antibacterial Anticancer Antifungal Antiparasitic standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11588
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept i2APP
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR
Physicochemical Analysis
C172H296N64O46S8
AQIFPSW
R
4253.12
10.01
11
2
9
+8
7.59
-0.720
52.86
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
3355
78.88
12
Residue Composition
number
0
A
8
R
1
N
1
D
6
C
1
E
0
Q
3
G
1
H
0
I
4
L
2
K
2
M
0
F
0
P
0
S
3
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 8 N: 1 D: 1 C: 6 E: 1 Q: 0 G: 3 H: 1 I: 0 L: 4 K: 2 M: 2 F: 0 P: 0 S: 0 T: 3 W: 0 Y: 2 V: 1
Chemical Descriptors
35
C172H296N64O46S8
4253.12
10.01
+8
7.59
-0.720
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli. ALso killed S. aureus based on virtual colony count assays (2.3 ug/ml killed 50% 9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). The original was merged with AP479. Updated 7/2021 2/2023
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli. ALso killed S. aureus based on virtual colony count assays (2.3 ug/ml killed 50% 9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). The original was merged with AP479. Updated 7/2021 2/2023
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

active against E. coli. ALso killed S. aureus based on virtual colony count assays (2.3 ug/ml killed 50% 9.8 ug/ml killed 99.9%). This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). The original was merged with AP479. Updated 7/2021 2/2023