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Peptide record

TPDB11587

Antibacterial Anticancer Antifungal Antiparasitic Neurotoxin Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11587
Antibacterial Anticancer Antifungal Antiparasitic Neurotoxin Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept NTxPred2 ToxinPred 3.0
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGSLFKFLAKKVAKTVAKQAAKQGAKYIANKQTE
Physicochemical Analysis
C174H285N47O46
RDCHMPW
K
3771.46
10.78
8
1
16
+7
5.73
-0.340
70.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
39.51
8
Residue Composition
number
7
A
0
R
1
N
0
D
0
C
1
E
3
Q
3
G
0
H
1
I
2
L
8
K
0
M
3
F
0
P
1
S
2
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 3 G: 3 H: 0 I: 1 L: 2 K: 8 M: 0 F: 3 P: 0 S: 1 T: 2 W: 0 Y: 1 V: 2
Chemical Descriptors
35
C174H285N47O46
3771.46
10.78
+7
5.73
-0.340
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Has antimicrobial activity against E.coli, E.faecalis, P.aeruginosa, and S.aureus. {ECO:0000269|PubMed:11792701}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Cupiennius salei (American wandering spider)
Neurotoxin
Has antimicrobial activity against E.coli, E.faecalis, P.aeruginosa, and S.aureus..
Cupiennin-1c (Cu-1c) (M-ctenitoxin-Cs1c) (M-CNTX-Cs1c)
spider
Cationic peptide 04 (cupiennin) family, 01 subfamily
Evidence at protein level
Amidation Antibiotic Antimicrobial Cytolysis Direct protein sequencing Hemolysis Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
Additional Detail Fields 7 fields
Amidation Antibiotic Antimicrobial Cytolysis Direct protein sequencing Hemolysis Neurotoxin Secreted Toxin
Neurotoxin
Evidence at protein level
Cationic peptide 04 (cupiennin) family, 01 subfamily
Cupiennin-1c (Cu-1c) (M-ctenitoxin-Cs1c) (M-CNTX-Cs1c)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
spider