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Peptide record

TPDB11585

Antibacterial Antifungal Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11585
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 35-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
ACDFQQCWVTCQRQYSINFISARCNGDSCVCTFRT
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C170H257N51O53S6
EHLKMP
C
4055.58
7.62
3
2
11
+1
2.12
-0.120
44.57
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
7365
1.82
19
Residue Composition
number
2
A
3
R
2
N
2
D
6
C
0
E
4
Q
1
G
0
H
2
I
0
L
0
K
0
M
3
F
0
P
3
S
3
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 2 D: 2 C: 6 E: 0 Q: 4 G: 1 H: 0 I: 2 L: 0 K: 0 M: 0 F: 3 P: 0 S: 3 T: 3 W: 1 Y: 1 V: 2
Chemical Descriptors
35 reviewed residue count
C170H257N51O53S6 sequence-only estimate (linear, free termini)
4055.58 sequence-only estimate (linear, free termini)
7.62 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
2.12 sequence-only estimate (linear, free termini)
-0.120 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cloning and purification of the first termicin-like peptide from the cockroach Eupolyphaga sinensis. | J Venom Anim Toxins Incl Trop Dis | 2016