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Peptide record

TPDB11579

Antibacterial Anticancer Antifungal Antiparasitic standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11579
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LRDLVCYCRKRGCKRRERMNGTCRKGHLMYTLCCR
Physicochemical Analysis
C174H301N65O45S8
AQIFPSW
R
4280.19
10.23
12
2
9
+9
8.44
-0.811
52.86
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
3355
78.38
11
Residue Composition
number
0
A
8
R
1
N
1
D
6
C
1
E
0
Q
3
G
1
H
0
I
4
L
3
K
2
M
0
F
0
P
0
S
2
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 8 N: 1 D: 1 C: 6 E: 1 Q: 0 G: 3 H: 1 I: 0 L: 4 K: 3 M: 2 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 2 V: 1
Chemical Descriptors
35
C174H301N65O45S8
4280.19
10.23
+9
8.44
-0.811
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli. ALso killed E. coli (99.9% killing at 5.6 ug/ml) and S. aureus (99.9% killing at 4.8 ug/ml) based on virtual colony count assays. This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). Updated 7/2021 2/2023
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli. ALso killed E. coli (99.9% killing at 5.6 ug/ml) and S. aureus (99.9% killing at 4.8 ug/ml) based on virtual colony count assays. This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). Updated 7/2021 2/2023
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against E. coli. ALso killed E. coli (99.9% killing at 5.6 ug/ml) and S. aureus (99.9% killing at 4.8 ug/ml) based on virtual colony count assays. This method exposed bacteria to peptides for 2 h in 10 mM phospahtate buffer before incubating in media for 12 h ( Wang et al., 2023 ). Updated 7/2021 2/2023