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Peptide record

TPDB11567

Antibacterial Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11567
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFP
Physicochemical Analysis
C204H310N62O37
ANDCEQHKMSTWV
P
4223.10
12.94
9
0
8
+9
8.06
-1.317
33.43
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
35.28
1
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
0
K
0
M
4
F
17
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 0 F: 4 P: 17 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
35
C204H310N62O37
4223.10
12.94
+9
8.06
-1.317
Evidence Records 1 records
Evidence 1 Activity

Activity

24.72% Cytotoxicity
Toxicity
64 µg/mL
Cytotoxic
24.72% Cytotoxicity | 64 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Copy number variation of PR-39 cathelicidin, and identification of PR-35, a natural variant of PR-39 with reduced mammalian cytotoxicity. | Gene | 2019