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Peptide record

TPDB11562

Antibacterial Antifungal Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11562
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 35-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SILSTLKDVGISALKNAGSGVLKTLLCKLNKNCEK
Physicochemical Analysis
C159H284N44O49S2
RQHMFPWY
L
3660.39
9.98
6
2
13
+4
6.06
0.169
122.57
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
3.41
11
Residue Composition
number
2
A
0
R
3
N
1
D
2
C
1
E
0
Q
3
G
0
H
2
I
7
L
6
K
0
M
0
F
0
P
4
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 1 C: 2 E: 1 Q: 0 G: 3 H: 0 I: 2 L: 7 K: 6 M: 0 F: 0 P: 0 S: 4 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
35
C159H284N44O49S2
3660.39
9.98
+4
6.06
0.169
Evidence Records 4 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
0% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
5% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 3 Activity

Activity

12% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
12% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014
Evidence 4 Activity

Activity

20% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
20% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus. | Biochimie | 2014