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Peptide record

TPDB11557

Antibacterial Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB11557
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
GKGALKKFLAKKVAKTVAKQAAKQGAKYVVNKQME
Physicochemical Analysis
C170H295N49O44S1
RDCHIPSW
K
3761.57
10.91
10
1
16
+9
9.92
-0.514
75.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
39.61
6
Residue Composition
number
7
A
0
R
1
N
0
D
0
C
1
E
3
Q
3
G
0
H
0
I
2
L
10
K
1
M
1
F
0
P
0
S
1
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 3 G: 3 H: 0 I: 0 L: 2 K: 10 M: 1 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 4
Chemical Descriptors
35
C170H295N49O44S1
3761.57
10.91
+9
9.92
-0.514
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>40 µM
Hemolytic Cytotoxic
50% Hemolysis | >40 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
N-terminal aromatic residues closely impact the cytolytic activity of cupiennin 1a, a major spider venom peptide. | Toxicon | 2013