Peptide record

TPDB11553

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB11553
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia Antifungipept CAFPdb AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GICACRRRFCPNSERFSGYCRVNGARYVRCCSRR
Physicochemical Analysis
C163H265N63O44S6
DQHLKMTW
R
4003.65
10.26
9
1
9
+8
4.93
-0.638
34.41
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
83.80
13
Residue Composition
number
2
A
9
R
2
N
0
D
6
C
1
E
0
Q
3
G
0
H
1
I
0
L
0
K
0
M
2
F
1
P
3
S
0
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 2 R: 9 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 0 K: 0 M: 0 F: 2 P: 1 S: 3 T: 0 W: 0 Y: 2 V: 2
Chemical Descriptors
34
C163H265N63O44S6
4003.65
10.26
+8
4.93
-0.638
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0-1.3 logs), S. epidermidis UCLA-622 (reduction 1.3 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A or III (reduction 0.3-0.6 logs), L. monocytogenes 450 (reduction 0.2 logs), P. aeruginosa PAO579 (reduction 3.3 logs), E. coli ATCC 29648 (reduction 0.6 logs), K. pneumoniae ATCC 13883 (reduction 2.4 logs), S. marcescens (reduction 0.5 log), H. influenzae Type 3A (reduction >1.1 log), B. bronchiseptica UCLA-342 (reduction 0.1 log).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0-1.3 logs), S. epidermidis UCLA-622 (reduction 1.3 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A or III (reduction 0.3-0.6 logs), L. monocytogenes 450 (reduction 0.2 logs), P. aeruginosa PAO579 (reduction 3.3 logs), E. coli ATCC 29648 (reduction 0.6 logs), K. pneumoniae ATCC 13883 (reduction 2.4 logs), S. marcescens (reduction 0.5 log), H. influenzae Type 3A (reduction >1.1 log), B. bronchiseptica UCLA-342 (reduction 0.1 log).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0-1.3 logs), S. epidermidis UCLA-622 (reduction 1.3 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A or III (reduction 0.3-0.6 logs), L. monocytogenes 450 (reduction 0.2 logs), P. aeruginosa PAO579 (reduction 3.3 logs), E. coli ATCC 29648 (reduction 0.6 logs), K. pneumoniae ATCC 13883 (reduction 2.4 logs), S. marcescens (reduction 0.5 log), H. influenzae Type 3A (reduction >1.1 log), B. bronchiseptica UCLA-342 (reduction 0.1 log).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
log deduction after 20 min incubation with 50 ug/ml peptide. Active against S. aureus strains 566, 502A, J.F. (reduction 0-1.3 logs), S. epidermidis UCLA-622 (reduction 1.3 logs), S. pneumoniae Type III (reduction >3.5 log), S. agalactiae Type I-A or III (reduction 0.3-0.6 logs), L. monocytogenes 450 (reduction 0.2 logs), P. aeruginosa PAO579 (reduction 3.3 logs), E. coli ATCC 29648 (reduction 0.6 logs), K. pneumoniae ATCC 13883 (reduction 2.4 logs), S. marcescens (reduction 0.5 log), H. influenzae Type 3A (reduction >1.1 log), B. bronchiseptica UCLA-342 (reduction 0.1 log).